DNA replication is initiated upon binding of "initiators" to origins Knee Walker of replication.In simian virus 40 (SV40), the core origin contains four pentanucleotide binding sites organized as pairs of inverted repeats.Here we describe the crystal structures of the origin binding domain (obd) of the SV40 large T-antigen (T-ag) both with and with
In the present paper, the process of designing launch abort system is presented for manned spacecraft in sub-orbital mission.For this purpose, by studying the other manned spacecraft launch abort system, a number of dimensionless parameters have been generated Frais de dossier for the launch abort system and spacecraft.using these parameters, the m
Plant fungal diseases cause up to 15-20% and, in extreme cases, up to 60% yield loss globally.The use of chemical pesticides for the suppression of fungal plant diseases has many negative consequences for the environment.Therefore, new alternatives to suppress fungal pathogens are actively sought.In this present study, biosurfactants produced by th
Bacterial conjugation is the main horizontal gene transfer route responsible for the spread of antibiotic resistance, virulence and toxin genes.During conjugation, DNA is transferred from a donor to a recipient cell via a sophisticated channel connecting the two cells.Conjugation not only affects many different aspects of the plasmid and the host,
We study the dependence of salinity on temperature in two by two degrees latitude-longitude boxes, for surface and upper-thermocline waters of the eastern North Atlantic subtropical gyre.The initial data set, from historical databases as well as from KYOTO WHITE MISO recent hydrographic cruises in the region, is carefully scrutinized to reject dubi